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Rapid test for qualitative detection of cardiac Troponin I in serum, plasma or whole blood.
| - RELIABLE: |
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- Quality system certified ISO 9001 and ISO 13485.
- Sensitivity = 100% & Specificity = 82%. (Compared to RXL DADE Behring instrument).
- In a clinical study carried out on 113 patients, the 29 cases of recent myocardialinfarctions
have been correctly detected with TROPONITEST®.
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| - PRACTICAL: |
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- Realizable on serum, plasma, venous whole blood and capillary blood.
- No dilution buffer.
- Long shelf life : 24 months.
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| - SIMPLE: |
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- Packaging presentation : 10 tests per kit.
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| - EFFICIENT: |
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- Detection limit : 0.5 ng/ml.
- Fast : Results in 10 minutes.
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Cardiac Troponin I (cTnI) is a protein found in cardiac muscle with a molecular weight of 22.5 kDa. Troponin I is part of a three subunit complex comprising of Troponin T and Troponin C. Along with tropomyosin, this structural complex forms the main component that regulates the calcium sensitive ATPase activity of actomyosin in striated skeletal and cardiac muscle. After cardiac injury occurs, Troponin I is released into the blood 4-6 hours after the onset of pain. The release pattern of cTnI is similar to CK-MB, but while CK-MB levels return to normal after 72 hours, Troponin I remains elevated for 6-10 days, thus providing for a longer window of detection for cardiac injury.
The high specificity of cTnI measurements for the identification of myocardial damage has been demonstrated in conditions such as the perioperative period, after marathon runs, and blunt chest trauma. Because of its high specificity and sensitivity in the myocardial tissue, Troponin I has recently become the most preferred biomarker for myocardial infarctio .
The TROPONITEST® is a simple test that utilizes a combination of anti-cTnI antibody coated particles and capture reagent to selectively detect cTnI in whole blood, serum or plasma. The minimum detection level is 0.5 ng/mL.
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